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Juicing Vegetables Without Fruit Pulp

Juicing Vegetables Without Fruit Pulp Orange Juice Against Kidney Stones Ejuice Ever 2017 Best
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Sodalite: Headache Relief at Moment · Reiki Music Zone

Magic of Crystal Stones: Chakra Balancing, Zazen Meditation Healing Therapy, Colors of Aura

℗ 2018 Yogasphere Chill 99

Released on: 2018-09-13

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I am fucking done suffering.

Hi everyone! I’m new here but I am so so so happy I have found you guys.
I have been dealing with what I thought were “headaches” for years now. Until recently it was about once a week and now? About 4/5 times a week I’m experiencing cranium pain.
I’ve been seeing my doctor weekly trying to get this figured out. We thought it was muscles spasms causing headaches and that’s how we found out my insurance refuses to cover massage therapy. So the next week there I am back in the doctor’s office only this time a new symptom has appeared. Searing pain in my right eye that shoots back into my skull.
Now until this point I had tried ibuprofen, acetaminophen, aspirin, excedrine, caffeine, ice, even essential oils (I was desperate). The only thing that gave me a tiny amount of relief was an ice pack on my forehead and back of the neck, and that was just enough that I could fall asleep.
This is when my doc has a “eureka” moment and tells me these aren’t headaches, they’re migraines and we need to treat them VERY differently than the run of the mill headache.
Now we have a plan of attack.
She prescribed me Sumatriptan, wrote me a physical therapy referral, told me to get a supportive pillow (got today), and said it looks like I’m grinding my teeth so see the dentist (did today got fitted for a night guard), and get on a better sleep schedule.
If these things don’t help the next step is imaging. Though I am optimistic.
I’m going to make these migraines my bitch. I am so sick of suffering and hiding in the dark with my ice packs. And I am so happy I found a community of people who know what I’m going through!
I just took my first sumatriptan, migraine is currently coming on strong. Now laying on my new pillow in the dark with my blue light blocking glasses in and ice packs in place.
If anyone has additional tips for me I would love to hear them!

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11 Natural Cures For Pain

Thursday, December 06, 2018 11 Natural Cures For Pain All of us felt pain right from the time we’re young. What is the easy remedy for most, pop a pill that you can get over the counter. But, sadly, people at that point of time forget that the pill causes more harm than good. Over a period of time, the same pill won’t be effective to get relief from pain, as our body has got used to it. Then, people go for stronger pain killers, more harmful. In stead of popping pill each time even for a minor pain, why not try some home remedies or alternative therapies. Capsaicin Reduce pain from arthritis, shingles, or neuropathy What the science says: An active component of chili pepper, capsaicin temporarily desensitizes pain-prone skin nerve receptors called C-fibers; soreness is diminished for 3 to 5 weeks while they regain sensation. Nearly 40% of arthritis patients reduced their pain by half after using a topical capsaicin cream for a month, and 60% of neuropathy patients achieved the same after 2 months, according to a study. Patients decreased their migraine and cluster headache intensity after applying capsaicin cream inside their nostrils. How to try it: Capsaicin ointments and creams are sold in pharmacies and health stores. For arthritis or neuropathy, try 0.025% or 0.075% capsaicin cream one to four times daily; best results can take up to 2 weeks, says a professor. But research on capsaicin and headaches remains limited–and don’t expect stronger versions anytime soon: “Current formulations are better suited for more acute problems, like a sore muscle or an arthritis flare-up, than everyday pain and stiffness,” the Prof. says. InflaThera or Zyflamend Help ease arthritis What the science says: Both supplement brands contain ginger, turmeric, and holy basil, all of which have anti-inflammatory properties. Turmeric (a curry ingredient) may be the best: A component, curcumin, eases inflammatory conditions like rheumatoid arthritis and psoriasis, according to the researchers. Researchers are now testing Zyflamend in RA patients, but some experts are already sold: “Each herb has its own scientific database of evidence,” says a Dr. How to try it: ProThera, InflaThera’s maker, will only sell to health care professionals, so your doctor has to order it for you; that said, it’s reportedly stronger (and slightly cheaper) than Zyflamend. InflaThera’s suggested dosage is twice daily with food. For the more readily accessible Zyflamend, take one capsule two or three times daily, but avoid it near bedtime–each pill contains 10 mg of caffeine (another version, Zyflamend PM, is reportedly less stimulating). Or, save money and try curcumin to start: Taking 500 mg four times daily, along with fish oil and a diet low in animal fat, can ease arthritis, says a Dr. Arnica Alleviate acute injury or post surgery swelling What the science says: This herb comes from a European flower; although its healing mechanism is still unknown, it does have natural anti-inflammatory properties. Taking oral homeopathic arnica after a tonsillectomy decreases pain, say researchers, and doctors found that it reduces surgery-related knee swelling. How to try it: Use homeopathic arnica as an adjunct to ice, herbs, or conventional pain meds, suggests a Dr. Rub arnica ointment on bruises or strained muscles, or take it in the form of three lactose pellets under the tongue up to six times per day. Aquamin Relieve osteoarthritis inflammation and pain What the science says: This red seaweed supplement is rich in calcium and magnesium. A preliminary clinical study showed that the ingredients may reduce joint inflammation or even help build bone, says researchers. In a study of 70 volunteers, Aquamin users reduced arthritis pain by 20% in a month, and had less stiffness than patients taking a placebo. How to try it: A Dr. recommends 2,400 mg a day (two capsules) of Aquamin in tablet form, sold domestically in products such as Aquamin Sea Minerals and Cal-Sea-Um. SAM-e (S adenosylmethionine) Reduce osteoarthritis aches What the science says: SAM-e is made from a naturally occurring amino acid and sold as capsules. Doctors aren’t entirely sure why it tamps down pain, but it reduces inflammation and may increase the feel-good brain chemicals serotonin and dopamine. Studies showed that SAM-e was as effective as some NSAIDs in easing osteoarthritis aches; the researchers found that SAM-e quashed pain by 50% after 2 months, though it took a few weeks to kick in. SAM-e produced no cardiovascular risks and fewer stomach problems than the conventional meds. How to try it: A Dr. prescribes 400 to 1,600 mg daily, often with turmeric or fish oil. SAM-e can interact with other meds, especially MAO-inhibitor antidepressants, so it’s vital to talk with your doctor before taking it (and avoid SAM-e entirely if you have bipolar disorder). Also, inspect the packaging before buying, he advises. Make sure the product carries a USP or GMP quality seal, contains a stabilizing salt, has a far-off expiration date, and comes in foil blister packs–SAM-e can degrade rapidly in direct light. Fish oil Relieve joint pain from arthritis or autoimmune disorders What the science says: Digested fish oil breaks down into hormone like chemicals called prostaglandins, which reduce inflammation. In one study, about 40% of rheumatoid arthritis patients who took cod-liver oil every day were able to cut their NSAID use by more than a third, some scientists recently reported. People with neck and back pain have fared even better: After about 10 weeks, nearly two-thirds were able to stop taking NSAIDs altogether in a study. How to try it: Taking 1,000 mg is proven to help your heart, but you should up the dose for pain. For osteoarthritis, try 2,000 to 4,000 mg daily; for rheumatoid arthritis and autoimmune diseases associated with joint pain (such as lupus), consider a much higher dose of upwards of 8,000 mg daily–but ask your doctor about such a large amount first, says a Dr. (The same rule applies if you take BP or heart meds, as omega-3s can thin the blood.) Read the nutrition label carefully: The dosage refers to the amount of omega-3s in a capsule, not other ingredients. Methylsulfonyl-methane (MSM) Improve osteoarthritis What the science says: MSM is derived from sulfur and may prevent joint and cartilage degeneration, say scientists. People with osteoarthritis of the knee who took MSM had 25% less pain and 30% better physical function at the end of a 3-month trial. Researchers also found that MSM worked better when combined with glucosamine. How to try it: Start with 1.5 to 3 g once daily and increase to 3 g twice daily for more severe pain, suggests a professor of clinical sciences. Patients in the Indian trial improved on dosages as low as 500 mg three times daily. Counting out loud Soothe brief “needle stick” pain What the science says: Patients who counted backward from 100 out loud during an injection experienced and recalled less pain, according to a recent study. None of the 46 patients who counted complained afterward, and only one of them could remember pain from the injection at all (among the 46 who didn’t count, 19 said the injection hurt and 10 recalled what it felt like). Recitation might work by distracting the brain from processing the sensation, says study author. The trick is probably only useful for short or acute periods, she says, adding: “The degree of pain reduction really depends on how well patients concentrate on counting.” Qigong Ease fibromyalgia or arthritis What the science says: Qigong is an umbrella term for traditional Chinese-medicine exercises or techniques that integrate body, posture, mind and breathing to improve the flow of energy, or qi. Women with severe fibromyalgia reported 73% less pain after just 5-7 sessions with a qigong master, according to a study, and the benefits continued three months later. “I’ve never seen pain scores change so dramatically,” says study co-author, who notes that larger trials need to be conducted to confirm these benefits. In other research, when qigong was combined with meditation, the pair helped patients reduce their pain as well as prescription drugs, according to researchers. And 83% of rheumatoid arthritis patients who practiced qigong for 1-2 hours a day reported greater improvement compared to 57% who received medication, Chinese doctors found. How to try it: A skilled practitioner can help you reduce your discomfort in 3 to 9 treatments, says a Master. Start off with a class or use an at-home video “Qigong Beginning Practice” at least one hour a day, either first thing in the morning or right before bed. Once you’ve got the hang of it, 20 to 30 minutes a day can keep pain at bay, says the study author. Acupuncture Relieve arthritis; migraines; low-back, menstrual, or post-operative pain What the science says: When pricked with tiny, essentially painless needles, your body releases endogenous opioids, its natural painkillers—but for reasons scientists are still figuring out, the benefits last longer than the chemicals’ analgesic effect. Recent research has yielded stunning results: people with knee arthritis reduced pain by 40% after 6 months of acupuncture that began as twice weekly sessions and was gradually reduced to once a month, according to researchers, who also found it can relieve low-back pain. Overseas, scientists in Europe used acupuncture to cut medication use in half among migraine sufferers—and, in another study, ease menstrual pain. Post-surgery patients needed less morphine after receiving the needle pricks, a recent review found. How to try it: For acute pain, try 5-8 treatments; experts say you’ll need 8-15 sessions for chronic pain . Glucosamine and chondroitin Protect cartilage from osteoarthritis What the science says: Glucosamine is a natural compound used in the formation and repair of cartilage, according to the Mayo Clinic. Chondroitin is made from shark and cow cartilage. Both are thought to help build or protect joint-cushioning cartilage—the same material that breaks down in osteoarthritis. The combination can help people with moderate to severe knee osteoarthritis, according to a study: 53% of users felt their pain decrease by half. How to try it: Take 500 mg of glucosamine three times a day alone or with 400 mg of chondroitin sulfate. The Natural Medicines Comprehensive Database suggests glucosamine sulfate over glucosamine hydrochloride, though many brands contain both. //gscrochetdesigns.blogspot.co m

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jQuery(‘.myCustomOption13_r_2’).click(function(){
jQuery(‘.myCustomOption13_error’).remove();
jQuery(‘.myCustomOption13’).append(“

Infections affecting more than 2 toenails may need enhanced treatments and may not improve with Curanail alone, please book to see your own GP or Podiatrist for further investigation and treatment.

“);
});
jQuery(‘.myCustomOption13_r_1’).click(function(){
jQuery(‘.myCustomOption13_error’).remove();
});
jQuery(‘.myCustomOption14_r_2’).click(function(){
jQuery(‘.myCustomOption14_error’).remove();
jQuery(‘.myCustomOption14’).append(“

Conditions listed above need careful monitoring and fungal nail infections can indicate poor control of the disorder, please book to see your GP or diabetic nurse as soon as possible.

“);
});
jQuery(‘.myCustomOption14_r_1’).click(function(){
jQuery(‘.myCustomOption14_error’).remove();
});
jQuery(‘.myCustomOption15_r_2’).click(function(){
jQuery(‘.myCustomOption15_error’).remove();
jQuery(‘.myCustomOption15’).append(“

Please book to see GP for treatment as this product is not proven to be safe during pregnancy or breast-feeding.

“);
});
jQuery(‘.myCustomOption15_r_1’).click(function(){
jQuery(‘.myCustomOption15_error’).remove();
});
jQuery(‘.myCustomOption16_r_1’).click(function(){
jQuery(‘.myCustomOption16_error’).remove();
jQuery(‘.myCustomOption16’).append(“

If the conditions above are not agreed to or met, then this treatment is not suitable.

“);
});
jQuery(‘.myCustomOption16_r_2’).click(function(){
jQuery(‘.myCustomOption16_error’).remove();
});
jQuery(‘.myCustomOption22_r_1’).click(function(){
jQuery(‘.myCustomOption22_error’).remove();
jQuery(‘.myCustomOption22’).append(“

If the conditions above are not agreed to or met, then this treatment is not suitable.

“);
});
jQuery(‘.myCustomOption22_r_2’).click(function(){
jQuery(‘.myCustomOption22_error’).remove();
});
jQuery(“.myCustomOption17 input:text”).focusout(function(){
if(this.value <= 27) {
jQuery('.myCustomOption17_error').remove();
jQuery('.myCustomOption17').append("

You don’t meet the requirements to take Alli as they are not considered overweight.

“);
} else {
jQuery(‘.myCustomOption17_error’).remove();
}
if(jQuery(‘.custom_warning’).length) {
$(‘.spinner-wrapper’).hide();
$(‘#product-addtocart-button’).hide();
$(‘div.add-to-cart-buttons’).hide();
$(‘div.qty_err_msg’).hide();
} else {
$(‘.spinner-wrapper’).show();
$(‘#product-addtocart-button’).show();
$(‘div.add-to-cart-buttons’).show();
}
});
jQuery(“.myCustomOption26_sel”).change(function(){
selectedvals = jQuery(‘.myCustomOption26_sel option:selected’).text().trim();
if(selectedvals == “A BMI below 18.5” || selectedvals == “A BMI of 18.5 to 24.9”) {
jQuery(‘.myCustomOption26_error’).remove();
jQuery(‘.myCustomOption26’).append(“

We cannot supply you with this product as the answer provided indicates you are of a healthy weight.

“);
} else if(selectedvals == “A BMI of 24.9 to 28”) {
jQuery(‘.myCustomOption26_error’).remove();
jQuery(‘.myCustomOption26’).append(“

Your BMI shows that you are classed as slightly overweight and an altered diet would be more suitable than beginning medication such as Alli.

“);
} else {
jQuery(‘.myCustomOption26_error’).remove();
}
});
jQuery(‘.myCustomOption18_r_2’).click(function(){
jQuery(‘.myCustomOption18_error’).remove();
jQuery(‘.myCustomOption18’).append(“

This medication is not advised for use during pregnancy or breast-feeding. Please speak to your GP regarding treatment.

“);
});
jQuery(‘.myCustomOption18_r_1’).click(function(){
jQuery(‘.myCustomOption18_error’).remove();
});
jQuery(‘.myCustomOption19_r_2’).click(function(){
jQuery(‘.myCustomOption19_error’).remove();
jQuery(‘.myCustomOption19’).append(“

If you are taking any of the medicines listed then it is not suitable for you to use. Please book to see your GP for alternative weight loss treatments. For alternative advice on weight loss click here.

“);
});
jQuery(‘.myCustomOption19_r_1’).click(function(){
jQuery(‘.myCustomOption19_error’).remove();
});
jQuery(‘.myCustomOption20_r_2’).click(function(){
jQuery(‘.myCustomOption20_error’).remove();
jQuery(‘.myCustomOption20’).append(“

This medication acts during the absorption of fat from the gut. Absorption problems could complicate this process, please book to see your GP regarding weight loss treatment or alternatively click here for more info. (Link to NHS Choices)

“);
});
jQuery(‘.myCustomOption20_r_1’).click(function(){
jQuery(‘.myCustomOption20_error’).remove();
});
jQuery(‘.myCustomOption21_r_1’).click(function(){
jQuery(‘.myCustomOption21_error’).remove();
jQuery(‘.myCustomOption21’).append(“

If the conditions above are not agreed to or met, then this treatment is not suitable.

“);
});
jQuery(‘.myCustomOption21_r_2’).click(function(){
jQuery(‘.myCustomOption21_error’).remove();
});
jQuery(‘.myCustomOption23_r_1’).click(function(){
jQuery(‘.myCustomOption23_error’).remove();
jQuery(‘.myCustomOption23’).append(“

Regaine may still be supplied. Be advised that there is no clinic evidence supporting using Regaine for treatment of hair loss only in the temple area.

“);
});
jQuery(‘.myCustomOption23_r_2’).click(function(){
jQuery(‘.myCustomOption23_error’).remove();
});
jQuery(‘.myCustomOption24_r_1’).click(function(){
jQuery(‘.myCustomOption24_error’).remove();
jQuery(‘.myCustomOption24’).append(“

Unfortunately, we are unable to supply you with this treatment. If you require emergency contraception urgently, please visit the NHS Choices website to find a clinic near you.

“);
});
jQuery(‘.myCustomOption24_r_2’).click(function(){
jQuery(‘.myCustomOption24_error’).remove();
});
jQuery(‘.myCustomOptionImages_r_2’).click(function(){
jQuery(‘.myCustomOptionImages_error’).remove();
jQuery(‘.myCustomOptionImages’).append(“

The symptoms you have indicated show extensive fungal infection and damage to the nails, we would advise you to book in to see your GP or Podiatrist as soon as possible.

“);
});
jQuery(‘.myCustomOptionImages_r_3’).click(function(){
jQuery(‘.myCustomOptionImages_error’).remove();
jQuery(‘.myCustomOptionImages’).append(“

The symptoms you have indicated show extensive fungal infection and damage to the nails, we would advise you to book in to see your GP or Podiatrist as soon as possible.

“);
});
jQuery(‘.myCustomOptionImages_r_1’).click(function(){
jQuery(‘.myCustomOptionImages_error’).remove();
});
if ($(‘.myCustomOptionTerms’).length) { // check is div ukcheck is present if not leave alone
var optionID = $(‘.myCustomOptionTerms input[type=radio]’).attr(‘name’)
optionID = optionID.match(/d+/)[0];
var yesIdmyCustomOptionTerms = “options_” + optionID + “_1”;
var noIdmyCustomOptionTerms = “options_” + optionID + “_2”;
var ukYesmyCustomOptionTerms = document.getElementById(yesIdmyCustomOptionTerms); // id buttons for uk check
var ukNomyCustomOptionTerms = document.getElementById(noIdmyCustomOptionTerms); // id buttons for uk check
ukNomyCustomOptionTerms.onclick = function () {
$(‘.myCustomOptionTerms_error’).remove();
var comm_err = “If the conditions above are not agreed to or met, then this treatment is not suitable.”;
if(jQuery(this).parents(“div.option”).hasClass(“CustomErr8”)) {
var comm_err = “Unfortunately, we are unable to supply this product. Please consult your GP immediately.”;
}
$(‘.myCustomOptionTerms’).append(“

“+comm_err+”

“);
}
ukYesmyCustomOptionTerms.onclick = function () {
$(‘.myCustomOptionTerms_error’).remove();
}
}
NoScore5 = 0;
if ($(‘.myCustomOption5’).length) { // check is div ukcheck is present if not leave alone
var optionID = $(‘.myCustomOption5 input[type=radio]’).attr(‘name’)
optionID = optionID.match(/d+/)[0];
var yesIdmyCustomOption5 = “options_” + optionID + “_1”;
var noIdmyCustomOption5 = “options_” + optionID + “_2”;
var ukYesmyCustomOption5 = document.getElementById(yesIdmyCustomOption5); // id buttons for uk check
var ukNomyCustomOption5 = document.getElementById(noIdmyCustomOption5); // id buttons for uk check
ukNomyCustomOption5.onclick = function () {
NoScore5 = 1;
}
ukYesmyCustomOption5.onclick = function () {
NoScore5 = 0;
}
}
NoScore6 = 0;
if ($(‘.myCustomOption6’).length) { // check is div ukcheck is present if not leave alone
var optionID = $(‘.myCustomOption6 input[type=radio]’).attr(‘name’)
optionID = optionID.match(/d+/)[0];
var yesIdmyCustomOption6 = “options_” + optionID + “_1”;
var noIdmyCustomOption6 = “options_” + optionID + “_2”;
var ukYesmyCustomOption6 = document.getElementById(yesIdmyCustomOption6); // id buttons for uk check
var ukNomyCustomOption6 = document.getElementById(noIdmyCustomOption6); // id buttons for uk check
ukNomyCustomOption6.onclick = function () {
NoScore6 = 1;
}
ukYesmyCustomOption6.onclick = function () {
NoScore6 = 0;
}
}
NoScore7 = 0;
if ($(‘.myCustomOption7’).length) { // check is div ukcheck is present if not leave alone
var optionID = $(‘.myCustomOption7 input[type=radio]’).attr(‘name’)
optionID = optionID.match(/d+/)[0];
var yesIdmyCustomOption7 = “options_” + optionID + “_1”;
var noIdmyCustomOption7 = “options_” + optionID + “_2”;
var ukYesmyCustomOption7 = document.getElementById(yesIdmyCustomOption7); // id buttons for uk check
var ukNomyCustomOption7 = document.getElementById(noIdmyCustomOption7); // id buttons for uk check
ukNomyCustomOption7.onclick = function () {
NoScore7 = 1;
}
ukYesmyCustomOption7.onclick = function () {
NoScore7 = 0;
}
}
jQuery(“#options_11991_2”).click(function(){
$(‘.options_11991_error’).remove();
$(‘#options_11991_1’).parents(‘div.pErrPro’).append(“

Unfortunately, we are unable to supply you with this treatment. If you require emergency contraception urgently, please visit the NHS Choices website to find a clinic near you.

“);
});
jQuery(“#options_11991_1”).click(function(){
$(‘.options_11991_error’).remove();
});
jQuery(“.myCustomOptionImages_r_1_radimg”).click(function(){
jQuery(“.myCustomOptionImages_r_1”).click();
jQuery(“.myCustomOption5span”).remove();
jQuery(“.myCustomOptionImages dd ul”).append(“Selected Option: 1“);
});
jQuery(“.myCustomOptionImages_r_2_radimg”).click(function(){
jQuery(“.myCustomOptionImages_r_2”).click();
jQuery(“.myCustomOption5span”).remove();
jQuery(“.myCustomOptionImages dd ul”).append(“Selected Option: 2“);
});
jQuery(“.myCustomOptionImages_r_3_radimg”).click(function(){
jQuery(“.myCustomOptionImages_r_3”).click();
jQuery(“.myCustomOption5span”).remove();
jQuery(“.myCustomOptionImages dd ul”).append(“Selected Option: 3“);
});
/*
jQuery(“#options_12636_1”).click(function(){
jQuery(“#options-12636-container”).css(“color”,”red”);
jQuery(“#options-12636-container”).css(“font-size”,”14px”);
jQuery(“#options-12636-container”).html(“Unfortunately, we cannot supply you with this treatment, Please consult your GP.”);
});
jQuery(“#options_12636_2”).click(function(){
jQuery(“#options-12636-container”).html(“”);
});
jQuery(“#options_12640_1”).click(function(){
jQuery(“#options-12640-container”).css(“color”,”red”);
jQuery(“#options-12640-container”).css(“font-size”,”14px”);
jQuery(“#options-12640-container”).html(“Unfortunately, we cannot supply you with this treatment. Please consult your GP.”);
});
jQuery(“#options_12640_2”).click(function(){
jQuery(“#options-12640-container”).html(“”);
});
jQuery(“#options_12641_2”).click(function(){
jQuery(“#options-12641-container”).css(“color”,”red”);
jQuery(“#options-12641-container”).css(“font-size”,”14px”);
jQuery(“#options-12641-container”).html(“Please confirm that you/the intended user agree.”);
});
jQuery(“#options_12641_1”).click(function(){
jQuery(“#options-12641-container”).html(“”);
});
*/
var Hide_Add_toCart = 2;
jQuery(“div.pom-content div.option input:radio”).click(function(){
if(jQuery(“#options_12641_2”).is(“:checked”) || jQuery(“#options_12636_1”).is(“:checked”)) {
Hide_Add_toCart = 1;
} else {
Hide_Add_toCart = 2;
}
if(jQuery(“#options_12639_1”).is(“:checked”)) {
if(jQuery(“#options_12640_1”).is(“:checked”))
Hide_Add_toCart = 1;
}
if(Hide_Add_toCart == 2) {
jQuery(“div.pom-content div.product-options-bottom div.add-to-cart”).show();
} else {
jQuery(“div.pom-content div.product-options-bottom div.add-to-cart”).hide();
}
});
jQuery(“input[type=radio]”).click(function(){
TotalNoScore = NoScore5 + NoScore6 + NoScore7;
if(TotalNoScore > 1) {
$(‘.myCustomOption7_error’).remove();
$(‘.myCustomOption7’).append(“

You are not suitable for Migraine Relief

“);
} else {
$(‘.myCustomOption7_error’).remove();
}
if(jQuery(this).hasClass(“CustomNoStop_r_2”)) {
var IdNoStop = jQuery(this).parents(“ul”).attr(‘id’)+”_no_stop”;
jQuery(“.”+IdNoStop).remove();
jQuery(this).parents(“div.option”).append(“

You are not suitable for this product

“);
}
if(jQuery(this).hasClass(“CustomNoStop_r_1”)) {
var IdNoStop = jQuery(this).parents(“ul”).attr(‘id’)+”_no_stop”;
jQuery(“.”+IdNoStop).remove();
}
if(jQuery(this).hasClass(“CustomYesStop_r_1”)) {
var IdYesStop = jQuery(this).parents(“ul”).attr(‘id’)+”_yes_stop”;
jQuery(“.”+IdYesStop).remove();
jQuery(this).parents(“div.option”).append(“

You are not suitable for this product

“);
}
if(jQuery(this).hasClass(“CustomYesStop_r_2”)) {
var IdYesStop = jQuery(this).parents(“ul”).attr(‘id’)+”_yes_stop”;
jQuery(“.”+IdYesStop).remove();
}
if(jQuery(this).hasClass(“CustomYesStop_r_3”)) {
var IdYesStop = jQuery(this).parents(“ul”).attr(‘id’)+”_yes_stop”;
jQuery(“.”+IdYesStop).remove();
}
MyCustom9 = 0;
jQuery(“.myCustomOption9_r_1”).each(function(){
if(this.checked)
MyCustom9++;
});
if(MyCustom9 > 2) {
jQuery(“.customoption9_error”).remove();
jQuery(“div.myCustomOption9Last”).append(“

You are not suitable for this product

“);
} else {
jQuery(“.customoption9_error”).remove();
}
if(jQuery(this).hasClass(“YesStopMe_r_1”)) {
var IdYesStop = jQuery(this).parents(“ul.options-list”).attr(‘id’)+”_yes_stop”;
jQuery(“.”+IdYesStop).remove();
var comm_err = “Based on your answer provided, your condition would be best treated with a face to face consultation with your own GP and not via mail-order medical services. Please make an appointment at your earliest convenience, alternatively if you have selected the wrong answer please revisit the question.”;
if(jQuery(this).parents(“div.option”).hasClass(“CustomErr1”)) {
var comm_err = “These medications can potentially interact with Levonelle/EllaOne. We are unable to supply this product. Please consult your GP immediately.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr2”)) {
var comm_err = “Unfortunately, we are unable to supply this product. Please consult your GP immediately.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr4”)) {
var comm_err = “Morning after pills will not end a pre-existing pregnancy. To order this product for future use, please change your answer to ‘No’ and continue.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr10”)) {
var comm_err = “We are unable to supply you with treatment. You should consider a migraine treatment plan with your GP. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr11”)) {
var comm_err = “We are unable to supply you with treatment. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr12”)) {
var comm_err = “We are unable to supply you with treatment since this medication is not indicated for migraines that cause the symptoms above. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr14”)) {
var comm_err = “We are unable to supply you with treatment. You should discuss with your GP the possibility that ‘triptans’ could be causing coronary vasoconstriction or anaphylaxis”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr18”)) {
var comm_err = “We are unable to supply you with Regaine. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr22”)) {
var comm_err = “Maloff Protect should not be used in pregnancy or whilst breastfeeding unless advised by a doctor or other qualified prescriber. Advice the customer to make an appointment to discuss suitable antimalarial protection with their doctor.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr23”)) {
var comm_err = “If the customer experienced mild side effects, such as headache, nausea and vomiting, abdominal pain or diarroea, reassure them that these are common and should not last long. Make them aware that absorption of atovaquone may be reduced in users with diarrhoea or vomiting.
If the customer experienced severe allergic reactions or side effects, Maloff Protect is contraindicated. Advise them to make an appointment to discuss suitable antimalarial protection with their doctor.
Check if the adverse event was reported. All adverse drug reactions should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr24”)) {
var comm_err = “Maloff Protect should not be used by customers who are taking any of these medicines unless advised by a doctor or other qualified prescriber. Advise the customer to make an appointment to discuss suitable antimalarial protection with their doctor or other qualified prescriber.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr25”)) {
var comm_err = “There are special warnings and precautions regarding the diagnoses in question 6. Refer to the SmPC for full information, and advise the customer to make an appointment with their doctor or other qualified prescriber to discuss weather or not Maloff Protect is suitable for them”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr26”)) {
var comm_err = “The maximum duration of travel for which Maloff Protect can be supplied without prescription is 12 weeks (93 tablets). For longer duration of travel, advice should be sought from a doctor or other qualified prescriber.
Tell your pharmacist if you are taking any medication or have any diagnosed medical condition that is not listed above.
Please read the SmPC or PIL for full details of contradications, special warnings and precautions.”;
}
jQuery(this).parents(“div.option”).append(“

“+comm_err+”

“);
}
if(jQuery(this).hasClass(“YesStopMe_r_2”)) {
var IdYesStop = jQuery(this).parents(“ul.options-list”).attr(‘id’)+”_yes_stop”;
jQuery(“.”+IdYesStop).remove();
}
if(jQuery(this).hasClass(“NoStopMe_r_2”)) {
var IdNoStop = jQuery(this).parents(“ul.options-list”).attr(‘id’)+”_no_stop”;
jQuery(“.”+IdNoStop).remove();
var comm_err = “Based on your answer provided, your condition would be best treated with a face to face consultation with your own GP and not via mail-order medical services. Please make an appointment at your earliest convenience, alternatively if you have selected the wrong answer please revisit the question.”;
if(jQuery(this).parents(“div.option”).hasClass(“CustomErr3”)) {
var comm_err = “Please be aware that Levonelle/EllaOne is not 100% effective. You can still change your answer and continue.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr5”)) {
var comm_err = “Levonelle should NOT be requested by women with a BMI of 30 or above.
EllaOne will be more effective and should be ordered instead.
You can change your answer to ‘Yes’ and continue.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr6”)) {
var comm_err = “Levonelle and EllaOne should NOT be taken in the same menstrual cycle (period). You can change your answer to ‘Yes’ and continue.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr7”)) {
var comm_err = “Unfortunately, we are unable to supply this product. Please consult your GP immediately.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr9”)) {
var comm_err = “We are unable to supply you with treatment. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr13”)) {
var comm_err = “If you have not been diagnosed with migraines and used triptan medication with success before contact your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr15”)) {
var comm_err = “You must agree to this before continuing. If you need assistance contact customer support.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr16”)) {
var comm_err = “Regaine is only indicated for males aged between 18 and 49. Contact us to discuss alternative options.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr17”)) {
var comm_err = “We are unable to supply you with Regaine. Please consult your GP.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr19”)) {
var comm_err = “EHC can only be supplied to the intended user, it can only be shipped to the woman in question.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr20”)) {
var comm_err = “Maloff Protect is not available from the pharmacy for those under 18 years old. If the customer is under 18, advise them to talk to their doctor as they may be suitable for prescription Atovaquone/Proguanil.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr21”)) {
var comm_err = “The safety and effectiveness of Maloff Protect has not been established for prophylaxis of malaria in patients who weigh less than 40 kg. Advise the customer to make an appointment to discuss suitable antimalarial protection with their doctor.”;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr27”)) {
var comm_err = “It is advised that this product is only used as an addition to healthy eating and exercise. For more advice please follow
http://www.nhs.uk/livewell/healthy-eating/Pages/Healthyeating.aspx“;
} else if(jQuery(this).parents(“div.option”).hasClass(“CustomErr29”)) {
var comm_err = “Because you have not visited your GP regarding Nausea Cyclizine is not best for first line treatment. Please see your GP to confirm cause of nausea.”;
}
jQuery(this).parents(“div.option”).append(“

“+comm_err+”

“);
}
if(jQuery(this).hasClass(“NoStopMe_r_1”)) {
var IdNoStop = jQuery(this).parents(“ul.options-list”).attr(‘id’)+”_no_stop”;
jQuery(“.”+IdNoStop).remove();
}
if(jQuery(‘.custom_warning’).length) {
$(‘.spinner-wrapper’).hide();
$(‘#product-addtocart-button’).hide();
$(‘div.add-to-cart-buttons’).hide();
$(‘div.qty_err_msg’).hide();
} else {
$(‘.spinner-wrapper’).show();
$(‘#product-addtocart-button’).show();
$(‘div.add-to-cart-buttons’).show();
}
});
jQuery(“select”).change(function(){
if(jQuery(‘.custom_warning’).length) {
$(‘.spinner-wrapper’).hide();
$(‘#product-addtocart-button’).hide();
$(‘div.add-to-cart-buttons’).hide();
$(‘div.qty_err_msg’).hide();
} else {
$(‘.spinner-wrapper’).show();
$(‘#product-addtocart-button’).show();
$(‘div.add-to-cart-buttons’).show();
}
});
jQuery(“a.btn-add-prescription”).click(function () {
//if (/Mobi/.test(navigator.userAgent)) {
document.getElementById(‘pom’).scrollIntoView();
//}
});
});
function ChageMyCustomOptions(opt,cliclid) {
opt1 = opt.split(“_”);
if(opt1[0] == “Yes”) {
jQuery(“img.Yes_”+opt1[1]).attr(“src”,SITE_SKIN_URL+”images/yes-option.png”);
jQuery(“img.No_”+opt1[1]).attr(“src”,SITE_SKIN_URL+”images/no-option-u.png”);
} else {
jQuery(“img.Yes_”+opt1[1]).attr(“src”,SITE_SKIN_URL+”images/yes-option-u.png”);
jQuery(“img.No_”+opt1[1]).attr(“src”,SITE_SKIN_URL+”images/no-option.png”);
}
jQuery(“#”+cliclid).click();
}
function ChageMyCustomOptionsDefaultRadio(opt,cliclid,type=”) {
if(type == “checkbox”) {
//jQuery(“img.”+opt).attr(“src”,SITE_SKIN_URL+”images/radio-un-ticked-img.png”);
//alert(jQuery(“#”+cliclid).attr(‘checked’));
if(jQuery(“#”+cliclid).prop(“checked”) == true) {
jQuery(“#img_other_”+cliclid).attr(“src”,SITE_SKIN_URL+”images/radio-un-ticked-img.png”);
} else {
jQuery(“#img_other_”+cliclid).attr(“src”,SITE_SKIN_URL+”images/radio-ticked-img.png”);
}
jQuery(“#”+cliclid).click();
} else {
jQuery(“img.”+opt).attr(“src”,SITE_SKIN_URL+”images/radio-un-ticked-img.png”);
jQuery(“#img_other_”+cliclid).attr(“src”,SITE_SKIN_URL+”images/radio-ticked-img.png”);
jQuery(“#”+cliclid).click();
}
}
jQuery(“.spinner-inc”).click(function(){
alert(“in”);
});
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Delivers Positive Phase 3 Results with Rimegepant Zydis® Orally Dissolving Tablet (ODT): Rapid and Lasting Benefit for the Acute Treatment of Migraine

– Single dose, proprietary, rimegepant Zydis ODT formulation provided rapid onset of pain relief with numerical separation from placebo as early as 15 minutes and statistically significant by 60 minutes – Achieved statistical significance on regulatory co-primary endpoints of pain freedom (p < 0.0001) and freedom from most bothersome symptom (p = 0.0009) at 2 hours – Novel Zydis ODT formulation demonstrated superiority over placebo in 21 consecutive, prespecified, hierarchically-tested efficacy outcome measures – Differentiated efficacy and safety profile with rimegepant in all three pivotal Phase 3 trials provides robust support for planned new drug application submission in the first half of 2019
NEW HAVEN, Conn., Dec. 3, 2018 /PRNewswire/ — Biohaven ) today announced positive topline results from a randomized, controlled Phase 3 clinical trial (BHV3000-303 or Study 303) evaluating the efficacy and safety of its Zydis ® orally dissolving tablet (ODT) formulation of rimegepant, an oral calcitonin gene-related peptide (CGRP) receptor antagonist, for the acute treatment of migraine. In Study 303, rimegepant Zydis ODT statistically differentiated from placebo on the two co-primary endpoints as well as the first 21 consecutive primary and secondary outcome measures that were prespecified in hierarchical testing. Consistent with the two previous Phase 3 clinical trials, Study 303 met its co-primary registrational endpoints of pain freedom and freedom from most bothersome symptom (MBS) at 2 hours using a single dose (Table 1). Importantly, patients treated with the rimegepant Zydis ODT formulation began to numerically separate from placebo on pain relief as early as 15 minutes, and this difference was statistically significant at 60 minutes (p < 0.0001) (Figure 1). Additionally, a significantly greater percentage of patients treated with rimegepant Zydis ODT returned to normal functioning by 60 minutes as compared to placebo (p = 0.0025). Lasting clinical benefit was observed through 48 hours after a single dose of rimegepant on freedom from pain (p < 0.0001), pain relief (p < 0.0001), freedom from the most bothersome symptom (p = 0.0018), and freedom from functional disability (p < 0.0001). Superiority over placebo was also demonstrated in multiple other secondary endpoints. The vast majority of patients treated with rimegepant Zydis ODT (85%) did not use any rescue medications.
Table 1:Met Co-Primary Endpoints of Pain Freedom & Freedom from Most Bothersome Symptom
2 Hour Endpoint
Rimegepant
(N=669)
Placebo
(N=682)
Difference
p-value
Pain Freedom
21.2%
10.9%
10.3%
3x ULN in Study 303. Pooled liver function test results across the three pivotal trials (n=3,556) performed to date showed that rimegepant was similar to placebo with regard to aminotransferase (ALT or AST) levels above the upper limit of normal (ULN) and no patients experienced elevations in bilirubin > 2x ULN (Table 3).
Table 2:Pooled Adverse Event (AE) Safety Data: Rimegepant was Similar to Placebo Across Studies
AEs from Studies 301, 302 and 303 with an incidence ≥ 1%
Adverse Event
Rimegepant
N=1,771
Placebo
N=1,785
≥ 1 On-Study AE 1
252 (14.2%)
209 (13.2%)
Nausea
26 (1.5%)
15 (0.8%)
UTI
21 (1.2%)
12 (0.7%)
SAEs 2
3 (0.2%)
3 (0.2%)
1. No other individual AEs ≥ 1% in rimegepant treated subjects than those listed in table. Includes all AEs without attribution to drug relatedness.
2. No drug-related Serious Adverse Events (SAEs). Two of the subjects with SAE in rimegepant group and one in placebo group had not been dosed before onset of SAE.
Table 3:Pooled Liver Function Test (LFT) Profile: Rimegepant was Similar to Placebo Across Studies
Pooled LFT Results from Studies 301, 302, and 303*
ALT or AST
Rimegepant
N=1,771
Placebo
N=1,785
> ULN 1
48 (2.7%)
52 (2.9%)
> 3x ULN
2 (0.1%)
2 (0.1%)
> 5x ULN
1 (0.06%) 2
0
> 10x ULN
0
0
> 20x ULN
0
0
1 Upper limit of normal; ALT alanine aminotransferase; AST aspartate aminotransferase
2 AST elevation, Not Drug-Related as deemed by the investigator: subject newly initiated weight-lifting with laboratory results consistent with muscle injury
*AST/ALT Categories are not mutually exclusive; No bilirubin elevations > 2x ULN across Studies 301, 302 and 303
Vlad Coric, M.D., Chief Executive Officer of Biohaven, stated, “Fast-acting and long-lasting pain relief in an easy to use formulation is important to patients. Rimegepant provides these characteristics and we believe is the first oral CGRP receptor antagonist to report superiority over placebo on pain relief and return to normal functioning by 60 minutes. These results, combined with the previous data from the two prior Phase 3 trials, reinforce the potential of rimegepant to be an important new and differentiated option for the acute treatment of migraine.”
The double-blind, randomized, multicenter, Phase 3 outpatient trial treated 1,375 patients across sites in the United States. Patients were required to have at least a one-year history of migraine (with or without aura), consistent with a diagnosis according to the International Classification of Headache Disorders. The trial was designed to evaluate the efficacy and safety of rimegepant Zydis ODT formulation compared with placebo in the acute treatment of migraine. Patients were given a single 75 mg dose of rimegepant Zydis ODT or a matching placebo. They were instructed to take their study medication when they had a migraine which reached moderate or severe pain intensity.
Richard B. Lipton, M.D., Professor and Vice Chair of Neurology, and Director of the Montefiore Headache Center, at the Albert Einstein College of Medicine stated, “Migraine is a serious, incapacitating, and highly prevalent neurological disease affecting 15% of the population. People with migraine miss work and lose time with their families because of disabling pain and associated symptoms. The most widely used acute prescription drugs, triptans, have cardiovascular contraindications, do not work in everyone and have been associated with high recurrence rates in those who respond. Rimegepant Zydis ODT formulation is rapidly absorbed and has a long half-life. It is gratifying to see the attractive pharmacokinetic profile deliver on its promise in a randomized trial. If approved, rimegepant could potentially play an important role in helping people with migraine find relief from their pain and get back to what they need to do in their lives.”
Biohaven has an exclusive worldwide license agreement with Catalent U.K. Swindon Zydis Limited, a subsidiary of Catalent, Inc. (NYSE: CTLT ) (“Catalent”) to provide Catalent’s Zydis ODT formulation for the development of rimegepant. The agreement also provides exclusive rights for developing small molecule CGRP receptor antagonists with the Zydis ODT technology. Catalent’s proprietary Zydis ODT fast-dissolve formulation is a unique, freeze-dried, oral solid dosage form that dissolves rapidly in the mouth, without the need for water. With more than 20 products launched in 50 countries and a dispersion speed of three seconds or less, Zydis ODT is generally recognized as the world’s fastest and best-in-class orally dissolving tablet. Zydis is a registered trademark of R. P. Scherer Technologies, Inc.
Robert Croop, M.D., Chief Development Officer – Neurology at Biohaven commented, “We are very pleased with the performance of our novel rimegepant Zydis ODT and believe that this formulation enhances the benefits offered by rimegepant and heightens its potential to become a best-in-class agent for the acute treatment of migraine. The rimegepant Zydis ODT was designed to enable patients to experience relief wherever and whenever a migraine strikes. The results of Study 303 demonstrate the clinical utility of this novel formulation.”
Additional secondary and exploratory outcome measures from this study are anticipated to be presented at upcoming scientific meetings in 2019.
Conference Call and Webcast
Biohaven will host a conference call and webcast today, December 3, 2018, at 8:30 a.m. ET (5:30 a.m. PT) to discuss topline results from the Phase 3 clinical trial of Rimegepant Zydis Orally Dissolving Tablet (ODT). The call can be accessed by dialing 877-407-9120 (domestic) or 412-902-1009 (international). To access the audio webcast with slides, please visit the “Events & Presentations” page in the Investors section of the Company’s website at https://www.biohavenpharma.com/investors/news-events/events-presentations . An archive of today’s teleconference and webcast will be available on Biohaven’s website for 6 months following the call.
About Migraine
Migraine is both a widespread and disabling neurological disorder. The Migraine Research Foundation ranks migraine as the world’s third most prevalent illness, affecting approximately 36 million people or 1 out of 4 households in the United States. And the Global Burden of Disease Study 2015 rates migraine as the seventh highest specific cause of disability worldwide. More than 90% of people with migraine are unable to work or function normally during an attack. Current treatment approaches, such as triptans, can be limited by headache recurrence within 24 hours after taking migraine medication, as well as cardiovascular contraindications and warnings.
About Rimegepant
Rimegepant (formerly known as BHV-3000), Biohaven’s lead product candidate, is an orally available, selective and potent small molecule CGRP receptor antagonist. The company believes rimegepant has the potential to be a best-in-class CGRP receptor antagonist for the acute and preventive treatment of migraine with the ability to address important unmet needs. The efficacy and safety profile of rimegepant has been consistently established across four randomized controlled trials, now including three Phase 3 studies (ClinicalTrials.gov Identifiers: NCT03235479 (Study 301); NCT03237845 (Study 302), NCT03461757 (Study 303)) and a Phase 2b study (NCT01430442). The co-primary endpoints achieved in the Phase 3 trials are consistent with regulatory guidance from the U.S. Food and Drug Administration (FDA) and provide the basis for a planned submission of a new drug application (NDA) to the FDA in 2019.
About Biohaven
Biohaven is a clinical-stage biopharmaceutical company with a portfolio of innovative, late-stage product candidates targeting neurological diseases, including rare disorders. Biohaven has combined internal development and research with intellectual property licensed from companies and institutions including Bristol-Myers Squibb Company, AstraZeneca AB, Yale University, Catalent, Rutgers, ALS Biopharma LLC and Massachusetts General Hospital. Currently, Biohaven’s lead development programs include multiple compounds across its CGRP receptor antagonist, glutamate modulation, and myeloperoxidase inhibitor platforms. Biohaven’s common shares are listed on the New York Stock Exchange and traded under the ticker symbol BHVN. More information about Biohaven is available at www.biohavenpharma.com
Forward-Looking Statements
This news release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements involve substantial risks and uncertainties, including statements that are based on the current expectations and assumptions of the Company’s management. All statements, other than statements of historical facts, included in this press release, including the Company’s timing of the expected NDA submission for rimegepant and its potential to be an improved treatment option for the acute treatment of migraine, are forward-looking statements. The use of certain words, including “believe” and “will” and similar expressions, is intended to identify forward-looking statements. The Company may not actually achieve the plans and objectives disclosed in the forward-looking statements, and you should not place undue reliance on the Company’s forward-looking statements. Various important factors could cause actual results or events to differ materially from those that may be expressed or implied by our forward-looking statements, including that topline data is based on preliminary analysis of key efficacy and safety data, and such data could change following a more comprehensive review and evaluation of more extensive data from the trials that the Company has not yet received, and these preliminary conclusions may not accurately reflect the complete results of the clinical trials, and uncertainties relating to the timing for submitting an NDA and the potential regulatory approval of rimegepant. Additional important factors to be considered in connection with forward-looking statements are described in the “Risk Factors” section of the Company’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2018 and other filings Biohaven makes with the U.S. Securities and Exchange Commission from time to time. The forward-looking statements are made as of this date and the Company does not undertake any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
For further information, contact Dr. Vlad Coric, the Chief Executive Officer at Vlad.Coric@biohavenpharma.com
View original content to download multimedia: http://www.prnewswire.com/news-releases/biohaven-delivers-positive-phase-3-results-with-rimegepant-zydis-orally-dissolving-tablet-odt-rapid-and-lasting-benefit-for-the-acute-treatment-of-migraine-300758762.html
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